The U. S. Food and Drug Administration (FDA) is warning people with kidney disease to stop taking Cipro, a commonly prescribed antibiotic. Cipro is a broad-spectrum antibiotic that can treat many different bacterial infections, including anthrax, Rocky Mountain spotted fever, and other types of bacterial infections. It is also used to prevent and treat infections that can affect the kidneys, including:
The FDA does not have enough data for claims against Cipro and other antibiotics for specific infections. Cipro is not approved for the treatment of viral infections like cold sores, flu, or herpes. While the FDA acknowledges that this is an unmet medical need, it is not a drug for that. Cipro is used to treat bacterial infections in both adults and children. It is also used to treat infections caused by viruses such as colds, flu, and herpes. The agency does not have a specific list of medications for treating viral infections. However, some antiviral drugs are not considered safe for use in children.
Cipro is one of several widely-used antibiotic drugs that can be used to treat UTIs and bacterial infections. The FDA notes that Cipro can treat several different bacterial infections, including:
Cipro is an FDA-approved antibiotic that has been used to treat urinary tract infections in children and adults. It is effective against many different types of bacteria. Cipro can be used to treat UTIs in adults and children. It can also be used to treat infections caused by viruses in infants and children, such as cold sores. The drug may be prescribed to treat viral infections that are caused by bacteria called "urinary tract infections" (UTIs).
People who have a kidney infection can take Cipro, but it is not approved for the treatment of UTIs. The FDA has not approved Cipro for use in children, but some doctors and pharmacists have prescribed it to treat UTIs.
Cipro, also known as ciprofloxacin, is an antibiotic drug that can treat a variety of bacterial infections. Cipro works by interfering with the bacteria's ability to produce enzymes that cause their growth and multiplication to be inhibited. The drug's effects on the body can be seen in urine. The drug is most effective when it is given in the urine for more than three days. Cipro is not approved for use in children, but some doctors have prescribed it for children as young as 3 years old.
Cipro works by blocking the production of certain enzymes in the bacteria, helping them multiply and eliminate the bacteria. The drug may take time to begin working in the body. Cipro can take several days to reach peak effectiveness. It is important to be careful when taking Cipro, as it can cause side effects, including nausea, vomiting, and diarrhea. The FDA notes that there are no studies on the effects of cipro on renal function.
Cipro is not approved for use in children, but some doctors have prescribed it to treat certain infections.
Treatment of bacterial infections of the lungs, nose, ear, bones and joints, skin and soft tissue, kidney, bladder, abdomen, and genitals caused by ciprofloxacin-susceptible organisms. Infections may include urinary tract infection, prostatitis, lower respiratory tract infection, otitis media (middle ear infection), sinusitis, skin, bone and joint infections, infectious diarrhea, typhoid fever, and gonorrhea.
May be taken with or without food. May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.
Hypersensitivity to ciprofloxacin or other quinolones. History or risk of QT prolongation; known history of myasthenia gravis. Concomitant use with tizanidine.
Vomiting, Stomach pain, Nausea, Diarrhea
Patient with known or suspected CNS disorders, risk factors predisposing to seizures, or lower seizure threshold; history or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); positive family history of aneurysm disease, pre-existing aortic aneurysm or dissection and its risk factors (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); diabetes, previous tendon disorder (e.g. rheumatoid arthritis), G6PD deficiency. Renal and hepatic impairment. Elderly, children. Pregnancy and lactation.
Store between 20-25°C.
Quinolones
Hair lossDispersible oral suspension
Microbial spectrum of action: fluoroquinolone classMoloprim: generic name ciprofloxacinfloxacin multivitase inhibitor ciprofloxacinfloxacinfloxacinfloxacinfloxacinFlastilNot recommended for women. Not recommended for children under 12 years of age. Avoid close monitoring of menstrual period. Do not take if you have a history of QT prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, heart failure, MI, bradycardia, peripheral atherosclerotic vascular disease, arthritis, gout, liver or kidney disease, or a history of toxaemia. QT prolongation should always begin within the first 6 months of breastfeeding. QT prolongation usually occurs during use of other quinolone antibiotics. Use of other quinolones may also cause QT prolongation. Use of ciprofloxacin with other antibiotics may also lead to QTc prolongation. QTc prolongation may usually be reversible upon further antibiotic therapy. If you become aQT4 inhibitor, monitor closely for sudden torsade of the bipolar mania reaction. AvoidQT prolongation during or just after surgery or radiation. Use of ciprofloxacin with other antibiotics may also cause QT prolongation. AvoidQT prolongation when using other antibiotics. Avoid abrupt or prolonged prolongation of the QT interval. Do not take if you are on amiodarone or if you have a history of sudden torsade of the bipolar mania reaction. QT prolongation may usually be reversible upon further antibiotic therapy. QT prolongation may usually usually be reversible upon further antibiotic therapy.
Ophthalmic ciprofloxacin comes as a solution (liquid) to apply to the eyes. Ciprofloxacin ophthalmic solution is usually used often, between once every 15 minutes to once every four hours while awake for seven to 14 days or longer. Ciprofloxacin ophthalmic ointment is usually applied three times a day for two days and then twice a day for five days. Use ciprofloxacin ophthalmic at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Use ciprofloxacin ophthalmic exactly as directed. Do not use it more often than prescribed by your doctor.
You should expect your symptoms to improve during your treatment. Call your doctor if your symptoms do not go away or get worse, or if you develop other problems with your eyes during your treatment.
Use ophthalmic ciprofloxacin until you finish the prescription, even if you feel better. If you stop using ophthalmic ciprofloxacin too soon, your infection may not be completely cured and the bacteria may become resistant to antibiotics.
To instill the eye drops, follow these steps:
Wash your hands thoroughly with soap and water.
Check the dropper tip to make sure that it is not chipped or cracked.
Avoid touching the dropper tip against your eye or anything else; eyedrops and droppers must be kept clean.
While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.
Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
Brace the remaining fingers of that hand against your face.
While looking up, gently squeeze the dropper soa single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
Close your eye for two to three minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.
Place a finger on the tear duct and apply gentle pressure.
Wipe any excess liquid from your face with a tissue.
If you are to use more than one drop in the same eye, wait at least five minutes before instilling the next drop.
Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.
Wash your hands to remove any medication.
To apply the eye ointment, follow these instructions:
Avoid touching the tip of the tube against your eye or anything else; the tube tip must be kept clean.
Holding the tube between your thumb and forefinger, place it as near to your eyelid as possible without touching it.
Tilt your head backward slightly.
With your index finger, pull the lower eyelid down to form a pocket.
Squeeze a 1/2-inch (1.25cm) ribbon of ointment into the pocket made by the lower eyelid.
Blink your eye slowly; then gently close your eye for one to two minutes.
With a tissue, wipe any excess ointment from the eyelids and lashes. With another clean tissue, wipe the tip of the tube clean.
Replace and tighten the cap right away.
This drug may interact with:
Cariprazil (Ciloxan), other quinolone drugs.
Tamoxifen.
Treatment of bacterial infections of the lungs, nose, ear, bones and joints, skin and soft tissue, kidney, bladder, abdomen, and genitals caused by ciprofloxacin-susceptible organisms. Infections may include urinary tract infection, prostatitis, lower respiratory tract infection, otitis media (middle ear infection), sinusitis, skin, bone and joint infections, infectious diarrhea, typhoid fever, and gonorrhea.
May be taken with or without food. May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.
Hypersensitivity to ciprofloxacin or other quinolones. History or risk of QT prolongation; known history of myasthenia gravis. Concomitant use with tizanidine.
Vomiting, Stomach pain, Nausea, Diarrhea
Patient with known or suspected CNS disorders, risk factors predisposing to seizures, or lower seizure threshold; history or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); positive family history of aneurysm disease, pre-existing aortic aneurysm or dissection and its risk factors (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); diabetes, previous tendon disorder (e.g. rheumatoid arthritis), G6PD deficiency. Renal and hepatic impairment. Elderly, children. Pregnancy and lactation.
Store between 20-25°C.
Quinolones
Use in Women onlyUse in Women Only
Teratogenic activityAdults:250 mg. In children, 250 mg-400 mg:500 mg-1 g daily for 3 days. In children over 3 years, 250 mg-500 mg:125 mg-400 mg daily for 3 days. In women, 500 mg-1 g daily for 3 days. For pediatric patients:250 mg-400 mg; 500 mg-750 mg; 750 mg; 750 mg; 1 g daily for 7 days. The maximum dosing frequency is 2 doses per 2 years.
History of QT prolongation; known history of QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); pre-existing CNS disorders or risk of QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); MI; hypotension, circulatory collapse, thrombosis, myocardial infarction, stroke.
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